Osimertinib-associated cardiac dysfunction in epidermal growth factor receptor-mutant non-small cell lung cancer: a single-center three-case series requiring hospitalization

Background: Osimertinib is frequently used for epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC), whereas cardiotoxicity signals, including left ventricular ejection fraction (LVEF) decline, heart failure (HF), and corrected QT interval prolongation, have been documen...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Masao Takemura, Shun Inoue, Akari Neoi, Daisuke Yoshida, Nao Shibata, Kentaro Hara, Takami Kobayashi, Ikuo Wakamatsu, Kohei Taguchi, Kazue Umetsu, Shunichi Kouno, Kana Ikeda, Mitsuru Motegi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-01-01
coleção:	Respiratory Medicine Case Reports
Assuntos:	NSCLC EGFR mutation Osimertinib Drug-induced cardiotoxicity Heart failure Left ventricular ejection fraction
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213007126000596
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!