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Complement Susceptibility in Relation to Genome Sequence of Recent <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Isolates from Thai Hospitals

ABSTRACT The capacity to resist the bactericidal action of complement (C′) is a strong but poorly understood virulence trait in Klebsiella spp. Killing requires activation of one or more C′ pathways, assembly of C5b-9 membrane attack complexes (MACs) on the surface of the outer membrane (OM), and pe...

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Principais autores: Jessica Loraine, Eva Heinz, Jessica De Sousa Almeida, Oleksandr Milevskyy, Supayang P. Voravuthikunchai, Potjanee Srimanote, Pattarachai Kiratisin, Nicholas R. Thomson, Peter W. Taylor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018-12-01
coleção:mSphere
Assuntos:
Klebsiella pneumoniae
complement resistance
lipopolysaccharide
polysaccharide capsules
whole-genome sequencing
Acesso em linha:https://journals.asm.org/doi/10.1128/mSphere.00537-18
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