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Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

γδ T cells are generally considered innate‐like lymphocytes. Here the authors sequence human γδ T cell receptors (TCR) to show focusing of the private Vδ1 TCR repertoire, suggesting that, unlike Vδ2 T cells, the Vδ1 T cell compartment has adaptive attributes.

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Hlavní autoři: Martin S. Davey, Carrie R. Willcox, Stephen P. Joyce, Kristin Ladell, Sofya A. Kasatskaya, James E. McLaren, Stuart Hunter, Mahboob Salim, Fiyaz Mohammed, David A. Price, Dmitriy M. Chudakov, Benjamin E. Willcox
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2017-03-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/ncomms14760
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