Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues.

Cytosolic 5'-nucleotidase II (cN-II) regulates the intracellular nucleotide pools within the cell by catalyzing the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. Beside this physiological function, high level of cN-II expression is correlated with abnormal patient outcome when t...

全面介紹

書目詳細資料

Principais autores:	Franck Gallier, Perrine Lallemand, Maïa Meurillon, Lars P Jordheim, Charles Dumontet, Christian Périgaud, Corinne Lionne, Suzanne Peyrottes, Laurent Chaloin
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2011-12-01
叢編:	PLoS Computational Biology
在線閱讀:	http://europepmc.org/articles/PMC3234209?pdf=render
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!