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Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

ABSTRACT Hepatocellular carcinoma (HCC) remains a leading cause of cancer‐related mortality, particularly in advanced stages where therapeutic options are limited. Cancer‐associated fibroblasts (CAF) within the tumor microenvironment (TME) contribute significantly to tumor progression and represent...

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Principais autores: Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2026-04-01
coleção:Advanced Science
Assuntos:
cancer‐associated fibroblasts
hepatocellular carcinoma
nanogel
polycarbonates
siRNA delivery
Acesso em linha:https://doi.org/10.1002/advs.202510006
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