Overexpression of the lncRNA TUG1 regulates high-glucose-induced endocytic clearance dysfunction in HLSECs via the Wnt/β-catenin signaling pathway

Abstract Background Type 2 diabetes mellitus (T2DM) and metabolic-associated fatty liver disease (MAFLD) are linked to endocytic clearance dysfunction in liver sinusoidal endothelial cells (LSECs), which accelerates their synergistic progression. Long noncoding RNA TUG1 (lncRNA TUG1) bridges these t...

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Autores principales:	Yingying Li, Weiwen Ding, Qi Zhang, Rangbao Cheng, Jing Ju, Junyi Zhu, Lirong Wei, Qianqian Tian, Shuyue Wang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-12-01
Colección:	European Journal of Medical Research
Materias:	Endocytic clearance dysfunction MAFLD HLSECs Wnt/β-catenin pathway
Acceso en línea:	https://doi.org/10.1186/s40001-025-03722-w
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