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Advances of MnO2 nanomaterials as novel agonists for the development of cGAS-STING-mediated therapeutics

As an essential micronutrient, manganese plays an important role in the physiological process and immune process. In recent decades, cGAS-STING pathway, which can congenitally recognize exogenous and endogenous DNA for activation, has been widely reported to play critical roles in the innate immunit...

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Principais autores: Tangxin Zhang, Chunmiao Hu, Wenting Zhang, Yongdui Ruan, Yuhe Ma, Dongsheng Chen, Yuhe Huang, Shuhao Fan, Wensen Lin, Yifan Huang, Kangsheng Liao, Hongemi Lu, Jun-Fa Xu, Jiang Pi, Xinrong Guo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-04-01
Serier:Frontiers in Immunology
Fag:
MnO2 nanomaterials
manganese ions
cGAS agonist
cGAS-STING pathway
novel therapeutics
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1156239/full
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