Extracellular vesicle‐packaged lncRNA from cancer‐associated fibroblasts promotes immune evasion by downregulating HLA‐A in pancreatic cancer

Abstract Pancreatic ductal adenocarcinoma (PDAC) is characterised by immune evasion that contribute to poor prognosis. Cancer‐associated fibroblasts (CAFs) play a pivotal role in orchestrating the PDAC tumour microenvironment. We investigated the role of CAF‐derived extracellular vesicle (EV)‐packag...

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Autors principals:	Hanming Yao, Chengzhi Huang, Jinmao Zou, Weiling Liang, Yue Zhao, Kege Yang, Ziyi Zhong, Shurui Zhou, Jiajia Li, Yaqing Li, Lishu Xu, Kaihong Huang, Guoda Lian
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2024-07-01
Col·lecció:	Journal of Extracellular Vesicles
Matèries:	CAFs engineered extracellular vesicles immune evasion lncRNA MHC‐I pancreatic cancer
Accés en línia:	https://doi.org/10.1002/jev2.12484
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