Chk1 and the Host Cell DNA Damage Response as a Potential Antiviral Target in BK Polyomavirus Infection

The human BK polyomavirus (BKPyV) is latent in the kidneys of most adults, but can be reactivated in immunosuppressed states, such as following renal transplantation. If left unchecked, BK polyomavirus nephropathy (PyVAN) and possible graft loss may result from viral destruction of tubular epithelia...

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Manylion Llyfryddiaeth

Prif Awduron:	Lydia E. Hainley, Martina S. Hughson, Amithi Narendran, Ralph Smith, Justin Arthur, Alida Hayner-Buchan, David J. Conti, John M. Lehman, Thomas D. Friedrich
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2021-07-01
Cyfres:	Viruses
Pynciau:	polyomavirus BKPyV BKV DNA damage response Chk1 antiviral
Mynediad Ar-lein:	https://www.mdpi.com/1999-4915/13/7/1353
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!