Chk1 and the Host Cell DNA Damage Response as a Potential Antiviral Target in BK Polyomavirus Infection

The human BK polyomavirus (BKPyV) is latent in the kidneys of most adults, but can be reactivated in immunosuppressed states, such as following renal transplantation. If left unchecked, BK polyomavirus nephropathy (PyVAN) and possible graft loss may result from viral destruction of tubular epithelia...

Description complète

Détails bibliographiques

Auteurs principaux:	Lydia E. Hainley, Martina S. Hughson, Amithi Narendran, Ralph Smith, Justin Arthur, Alida Hayner-Buchan, David J. Conti, John M. Lehman, Thomas D. Friedrich
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2021-07-01
Collection:	Viruses
Sujets:	polyomavirus BKPyV BKV DNA damage response Chk1 antiviral
Accès en ligne:	https://www.mdpi.com/1999-4915/13/7/1353
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!