Icariin-loaded GelMa hydrogel encapsulated potassium sodium niobate biomimetic piezoelectric scaffold regulates macrophage polarization to accelerate bone defect repair

Large bone defects present significant clinical challenges due to limitations of current treatments including immune rejection, infection, and poor osteoinductive capacity. This study developed a novel biomimetic piezoelectric scaffold system combining 3D-printed potassium sodium niobate/nano-hydrox...

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Библиографические подробности
Главные авторы: Yongbin Wang, Han Zhang, Zhili Xu, Weihang Zhu, Sheng Chang, Jiahao Wei, Shuqing Chen, Yong Liu, Weiqing Kong, Jianwei Guo
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2025-12-01
Серии:Materials Today Bio
Предметы:
Bone defect repair
3D printing
Icariin
Macrophage polarization
Piezoelectric biological scaffolds
Immune microenvironment
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2590006425010476
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