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Modulation of β-Amyloid Fibril Formation in Alzheimer’s Disease by Microglia and Infection

Amyloid plaques are a pathological hallmark of Alzheimer’s disease. The major component of these plaques are highly ordered amyloid fibrils formed by amyloid-β (Aβ) peptides. However, whilst Aβ amyloid fibril assembly has been subjected to detailed and extensive analysis in vitro, these studies may...

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Autori principali: Madeleine R. Brown, Sheena E. Radford, Eric W. Hewitt
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020-11-01
Serie:Frontiers in Molecular Neuroscience
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Accesso online:https://www.frontiersin.org/articles/10.3389/fnmol.2020.609073/full
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