S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling

Background: Endogenous hydrogen sulfide (H2S) is emerging as a key signal molecule in the development of diabetic cardiomyopathy. The aim of this study was to explore the effect and underlying mechanism of S-propargyl-cysteine (SPRC), a novel modulator of endogenous H2S, on diabetic cardiomyopathy i...

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Principais autores:	Ye Li, Kui-Fang Xie, Ya-Hong Chang, Cheng Wang, Ying Chen, Ming-Jie Wang, Yi-Chun Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-09-01
coleção:	Frontiers in Cardiovascular Medicine
Assuntos:	S-propargyl-cysteine hydrogen sulfide diabetic cardiomyopathy insulin receptor signaling glucose uptake
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcvm.2021.737191/full
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