The effect of calorie-restriction along with thylakoid membranes of spinach on the gut-brain Axis Pathway and oxidative stress biomarkers in obese women with polycystic ovary syndrome: a Randomized, Double-blind, placebo-controlled clinical trial

Abstract Background Women with polycystic ovary syndrome (PCOS) have higher intestinal mucosal permeability, leading to the lipopolysaccharide (LPS) leakage and endotoxemia. This, in turn, leads to oxidative stress (OS) and neuro-inflammation caused by the gut-brain axis, affecting the neurotrophic...

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Principais autores:	Negin Nikrad, Mahdieh Abbasalizad Farhangi, Fatemeh Pourteymour Fard Tabrizi, Maryam Vaezi, Ata Mahmoudpour, Mehran Mesgari-Abbasi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-11-01
coleção:	Journal of Ovarian Research
Assuntos:	Polycystic ovary syndrome Thylakoids Obesity Spinacia oleracea Caloric restriction Brain-gut axis
Acesso em linha:	https://doi.org/10.1186/s13048-023-01288-x
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