Ethanolaminephosphate cytidylyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major.

Glycerophospholipids including phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are vital components of biological membranes. Trypanosomatid parasites of the genus Leishmania can acquire PE and PC via de novo synthesis and the uptake/remodeling of host lipids. In this study, we investigate...

Full description

Bibliographic Details

Main Authors:	Somrita Basu, Mattie C Pawlowic, Fong-Fu Hsu, Geoff Thomas, Kai Zhang
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science (PLoS) 2023-07-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.1011112
Tags:	Add Tag No Tags, Be the first to tag this record!