Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antitumoral Drugs Induced-Cytotoxicity in Human Colon Adenocarcinoma Cells

Diabetes and cancer are common, chronic, and potentially fatal diseases that frequently co-exist. Observational studies clearly indicate that the risk of several types of cancer is increased in diabetic patients and a number of cancer types have shown a higher mortality rate in patients with hypergl...

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Principais autores:	Loredana Bergandi, Eleonora Mungo, Rosa Morone, Ornella Bosco, Barbara Rolando, Sophie Doublier
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2018-08-01
叢編:	Frontiers in Pharmacology
主題:	hyperglycemia chemoresistance doxorubicin 5-fluorouracil cytotoxicity cell damage
在線閱讀:	https://www.frontiersin.org/article/10.3389/fphar.2018.00866/full
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