Código QR (código de barras bidimensional)

Identification and validation of synergistic drug strategies targeting macrophage polarization in triple-negative breast cancer via single-cell transcriptomics and deep learning

Triple-negative breast cancer (TNBC) presents therapeutic challenges due to its immunosuppressive tumor microenvironment (TME) and limited targeted options. Analyzing scRNA-seq data from 24 TNBC patients using integrated transcriptomics, machine-learning, and pseudo-time trajectory mapping, we devel...

ver descrição completa

Na minha lista:
Principais autores: Qi Qi, Wenhao Yang, Liang Li, Yuheng Tang, Yongzhi Chen, Hui Wang, Sun Yingjie, Jialin Shi, Samina Gul, Wenru Tang, Jianyu Pang, Xiaoli Xie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-09-01
coleção:Translational Oncology
Assuntos:
Triple-negative breast cancer
Tumor microenvironment
Macrophage polarization
ZBTB20
Combination therapy
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1936523325001883
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados