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Homeodomain interacting protein kinase 2 activation compromises endothelial cell response to laminar flow: protective role of p21(waf1,cip1,sdi1).

BACKGROUND: In the cardiovascular system, laminar shear stress (SS) is one of the most important source of endothelial protecting signals. Physical and chemical agents, however, including ionising radiations and anticancer drugs, may injure endothelial cells determining an increase in oxidative stre...

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Hlavní autoři: Stefania Mattiussi, Chiara Lazzari, Silvia Truffa, Annalisa Antonini, Silvia Soddu, Maurizio C Capogrossi, Carlo Gaetano
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2009-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC2719102?pdf=render
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