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Development and Validation of Stability-Indicating HPLC Methods for the Estimation of Lomefloxacin and Balofloxacin Oxidation Process under ACVA, H<sub>2</sub>O<sub>2</sub>, or KMnO<sub>4</sub> Treatment. Kinetic Evaluation and Identification of Degradation Products by Mass Spectrometry

The oxidation of lomefloxacin (LOM) and balofloxacin (BAL) under the influence of azo initiator of radical reactions of 4,4′-azobis(4-cyanopentanoic acid) (ACVA) and H<sub>2</sub>O<sub>2</sub> was examined. Oxidation using H<sub>2</sub>O<sub>2</sub> was performed at room temperature while using ACVA...

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Detalhes bibliográficos
Principais autores: Barbara Żuromska-Witek, Paweł Żmudzki, Marek Szlósarczyk, Anna Maślanka, Urszula Hubicka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-11-01
coleção:Molecules
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Acesso em linha:https://www.mdpi.com/1420-3049/25/22/5251
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