DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

ABSTRACT Gastric cancer remains a leading cause of cancer mortality worldwide, largely due to its high metastatic potential driven by epithelial‐mesenchymal transition (EMT). Here, we identify Deltex E3 ubiquitin ligase 3L (DTX3L) as a previously unrecognized tumor suppressor in gastric cancer. DTX3...

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Hauptverfasser:	Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2026-07-01
Schriftenreihe:	Advanced Science
Schlagworte:	DTX3L EMT gastric cancer SNAI1 ubiquitination
Online-Zugang:	https://doi.org/10.1002/advs.202524036
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