Notch Signaling Induced by Endoplasmic Reticulum Stress Regulates Cumulus-Oocyte Complex Expansion in Polycystic Ovary Syndrome

Endoplasmic reticulum (ER) stress activated in granulosa cells contributes to the pathophysiology of polycystic ovary syndrome (PCOS). In addition, recent studies have demonstrated that Notch signaling plays multiple roles in the ovary via cell-to-cell interactions. We hypothesized that ER stress ac...

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Bibliografische gegevens

Hoofdauteurs:	Hiroshi Koike, Miyuki Harada, Akari Kusamoto, Chisato Kunitomi, Zixin Xu, Tsurugi Tanaka, Yoko Urata, Emi Nose, Nozomi Takahashi, Osamu Wada-Hiraike, Yasushi Hirota, Kaori Koga, Yutaka Osuga
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2022-07-01
Reeks:	Biomolecules
Onderwerpen:	cumulus-oocyte complex expansion endoplasmic reticulum stress granulosa cell notch signaling polycystic ovary syndrome unfolded protein response
Online toegang:	https://www.mdpi.com/2218-273X/12/8/1037
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