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Selective reduction of oxo bile acids: synthesis of 3 beta-, 7 beta-, and 12 beta-hydroxy bile acids.

Preparation of some biologically important keto bile acids is described. Advantage is taken of the preferential ketalization of 3-oxo group in bile acids over 7- and 12-oxo groups for the selective reduction of these keto groups. The method was found to be specially useful for preparation of 7 beta-...

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Autors principals: AK Batta, SK Aggarwal, G Salen, S Shefer
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 1991-06-01
Col·lecció:Journal of Lipid Research
Accés en línia:http://www.sciencedirect.com/science/article/pii/S0022227520419947
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