New Insights into the Role of Phosphoinositide 3-Kinase Activity in the Physiology of Immature Oocytes: Lessons from Recent Mouse Model Studies

The immature oocytes within primordial follicles are arrested at Prophase I of meiosis and remain dormant until awakened by an increase in intracellular levels of phosphatidylinositol (3,4,5)-trisphosphate (PIP3). Oocyte PIP3 level is determined by the balance between the activity of phosphoinositid...

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Hlavní autoři:	So-Youn Kim, Takeshi Kurita
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	European Medical Journal 2018-06-01
Edice:	European Medical Journal
Témata:	follicle activation follicle loss glanulosa cell tumour mouse model phosphatase and tensin homologue (pten) phosphatidylinositol (3 4 5)-trisphosphate (pip3) phosphoinositide 3-kinase (pi3k) pathway
On-line přístup:	https://www.emjreviews.com/reproductive-health/article/new-insights-into-the-role-of-phosphoinositide-3-kinase-activity-in-the-physiology-of-immature-oocytes-lessons-from-recent-mouse-model-studies/
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