Restoration of Silenced Peutz-Jeghers Syndrome Gene, LKB1, Induces Apoptosis in Pancreatic Carcinoma Cells
Germ line mutations of the LKB1 tumor suppressor gene lead to Peutz-Jeghers syndrome (PJS) with a predisposition to cancer. Previous reports suggest that inactivation of this tumor-suppressor gene plays a role in the pathogenesis of gastrointestinal hamartomas as well as several cancers, including a...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2003-07-01
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| Serie: | Neoplasia: An International Journal for Oncology Research |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S1476558603800301 |
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