Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation

Diverse indoles and bis-indoles extracted from marine sources have been identified as promising anticancer leads. Herein, we designed and synthesized novel bis-indole series <b>7a</b>–<b>f</b> and <b>9a</b>–<b>h</b> as Topsentin and Nortopsentin analogs. Our design is based on replacing the heterocy...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Wagdy M. Eldehna, Ghada S. Hassan, Sara T. Al-Rashood, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Ghada H. Al-Ansary
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-04-01
Schriftenreihe:	Marine Drugs
Schlagworte:	marine-inspired breast cancer bis-indoles synthesis apoptosis
Online-Zugang:	https://www.mdpi.com/1660-3397/18/4/190
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!