Impact of a Complement Factor H Gene Variant on Renal Dysfunction, Cardiovascular Events, and Response to ACE Inhibitor Therapy in Type 2 Diabetes

Complement activation has been increasingly implicated in the pathogenesis of type 2 diabetes and its chronic complications. It is unknown whether complement factor H (CFH) genetic variants, which have been previously associated with complement-mediated organ damage likely due to inefficient complem...

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Hlavní autoři:	Elisabetta Valoti, Marina Noris, Annalisa Perna, Erica Rurali, Giulia Gherardi, Matteo Breno, Aneliya Parvanova Ilieva, Ilian Petrov Iliev, Antonio Bossi, Roberto Trevisan, Alessandro Roberto Dodesini, Silvia Ferrari, Nadia Stucchi, Ariela Benigni, Giuseppe Remuzzi, Piero Ruggenenti
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2019-07-01
Edice:	Frontiers in Genetics
Témata:	diabetes complement factor H ACE inhibitors microalbuminuria cardiovascular risk
On-line přístup:	https://www.frontiersin.org/article/10.3389/fgene.2019.00681/full
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