Myeloid HIF-1 attenuates the progression of renal fibrosis in murine obstructive nephropathy

Hypoxia-inducible factors (HIFs) play an important role in the pathogenesis of renal fibrosis. Although the role of macrophage infiltration in the progression of renal fibrosis is well known, the role of macrophage HIF-1 remains to be revealed. To address this question, myeloid specific conditional...

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Detalhes bibliográficos
Principais autores: Yu Tateishi, Mayuko Osada-Oka, Masako Tanaka, Masayuki Shiota, Yasukatsu Izumi, Eiji Ishimura, Koka Motoyama, Masaaki Inaba, Katsuyuki Miura
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-02-01
coleção:Journal of Pharmacological Sciences
Assuntos:
Hypoxia-inducible factor
Renal fibrosis
Macrophage
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1347861314000322
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