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Oncogenic LMO3 collaborates with HEN2 to enhance neuroblastoma cell growth through transactivation of Mash1.

Expression of Mash1 is dysregulated in human neuroblastoma. We have also reported that LMO3 (LIM-only protein 3) has an oncogenic potential in collaboration with neuronal transcription factor HEN2 in neuroblastoma. However, the precise molecular mechanisms of its transcriptional regulation remain el...

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Detalhes bibliográficos
Principais autores: Eriko Isogai, Miki Ohira, Toshinori Ozaki, Shigeyuki Oba, Yohko Nakamura, Akira Nakagawara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-05-01
Colecção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0019297
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