Structural and Functional Insight Into the Glycosylation Impact Upon the HGF/c-Met Signaling Pathway

Upon interactions with its specific ligand hepatocyte growth factor (HGF), the c-Met signal is relayed to series of downstream pathways, exerting essential biological roles. Dysregulation of the HGF-c-Met signaling pathway has been implicated in the onset, progression and metastasis of various cance...

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Detalhes bibliográficos

Principais autores:	Xinyue Hu, Feiyu Tang, Peilin Liu, Taowei Zhong, Fengyan Yuan, Quanyuan He, Mark von Itzstein, Hao Li, Liang Weng, Xing Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-06-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	HGF c-Met glycosylation cancer application
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fcell.2020.00490/full
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