Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology.

Rho-associated coiled coil containing protein kinase (Rho-kinase or Rock) is a well-defined determinant of actin organization and dynamics in most animal cells characterized to date. One of the primary effectors of Rock is non-muscle myosin II. Activation of Rock results in increased contractility o...

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Autores principales:	Swarna Mohan, Debamitra Das, Robert J Bauer, Annie Heroux, Jenna K Zalewski, Simone Heber, Atinuke M Dosunmu-Ogunbi, Michael A Trakselis, Jeffrey D Hildebrand, Andrew P Vandemark
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2013-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3857177?pdf=render
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