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Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a <i>Drosophila</i> Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterised by progressive degeneration of the motor neurones. An expanded <i>GGGGCC (G4C2)</i> hexanucleotide repeat in <i>C9orf72</i> is the most common genetic cause of ALS and frontotemporal dementia (FTD); therefo...

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Principais autores: Ella Dunn, Joern R. Steinert, Aelfwin Stone, Virender Sahota, Robin S. B. Williams, Stuart Snowden, Hrvoje Augustin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-08-01
Serier:Cells
Fag:
ALS
MCFA
4-MOA
NA
<i>Drosophila</i>
motor function
Online adgang:https://www.mdpi.com/2073-4409/12/17/2163
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