Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy

The clustering of L-type calcium channels (LTCC) for functional regulation of intracellular calcium signaling remains poorly understood. Here we applied super-resolution imaging to study CaV1.3 channel clusters in human iPSC-derived atrial cardiomyocytes (hiPSC-aCM) to analyze subcellular localizati...

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Detalhes bibliográficos

Principais autores:	Niko Schwenzer, Roman Tsukanov, Tobias Kohl, Samrat Basak, Izzatullo Sobitov, Fitzwilliam Seibertz, Rohan Kapoor, Niels Voigt, Jörg Enderlein, Stephan E. Lehnart
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-12-01
Colecção:	Journal of Molecular and Cellular Cardiology Plus
Assuntos:	CaV1.3 calcium channel L-type calcium channel Channel clustering Channel mobility Membrane nanodomain hiPSC-CM
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2772976125002090
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