PF573,228 inhibits vascular tumor cell growth, migration as well as angiogenesis, induces apoptosis and abrogates PRAS40 and S6RP phosphorylation
PF573,228 is a compound that targets focal adhesion kinase (FAK), a non-receptor protein kinase, which is over-expressed in various tumors. The aim of this study was to evaluate the effects of PF573,228 on the cells derived from mouse vascular tumors, namely, endothelioma cells.
Tallennettuna:
| Päätekijä: | |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Sciendo
2016-09-01
|
| Sarja: | Acta Pharmaceutica |
| Aiheet: | |
| Linkit: | https://doi.org/10.1515/acph-2016-0031 |
| Tagit: |
Ei tageja, Lisää ensimmäinen tagi!
|