Heterozygous females from a rat model for creatine transporter deficiency reveal altered behavioral response to stressors, normal body weight and slight metabolic changes

Creatine (Cr) is an organic acid essential for recycling ATP, important in tissues with high energy demand such as muscle or brain. Cr is synthesized in a 2-step pathway by the enzymes AGAT and GAMT, and transported by SLC6A8 (also called CrT). Cerebral Cr deficiency syndromes (CCDS), due to AGAT, G...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Lara Duran-Trio, Marc Lanzillo, Dunja Simicic, Clothilde Roux-Petronelli, Stephen J. Bruce, Carmen Sandi, Cristina Cudalbu, Olivier Braissant
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-04-01
Serie:	Frontiers in Neuroscience
Soggetti:	creatine creatine transporter deficiency SLC6A8 female X-linked disorder behavior
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1520550/full
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!