Impaired IgM Memory B Cell Function Is Common in Coeliac Disease but Conjugate Pneumococcal Vaccination Induces Robust Protective Immunity

Coeliac disease (CD) is associated with hyposplenism, an acquired impairment of spleen function associated with reduced IgM memory B cells and increased susceptibility to serious pneumococcal infection. Little is known about the immune implications of hyposplenism in CD or the optimal pneumococcal v...

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Detalhes bibliográficos

Principais autores:	Olivia G. Moscatelli, Amy K. Russell, Lee M. Henneken, Melinda Y. Hardy, Nadia Mazarakis, Rachel Higgins, Jesse Ekin, Harry McLeod, Paul Simkin, Paul V. Licciardi, Vanessa L. Bryant, Jason A. Tye-Din
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-02-01
coleção:	Vaccines
Assuntos:	coeliac disease IgM memory B cells hyposplenism pneumococcal vaccination
Acesso em linha:	https://www.mdpi.com/2076-393X/12/2/214
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