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Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription

Newly born cells either continue to proliferate or exit the cell division cycle. This decision involves delaying expression of Cyclin E that promotes DNA replication. ORC1, the Origin Recognition Complex (ORC) large subunit, is inherited into newly born cells after it binds to condensing chromosomes...

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Bibliografische gegevens
Hoofdauteurs: Manzar Hossain, Bruce Stillman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications Ltd 2016-07-01
Reeks:eLife
Onderwerpen:
Online toegang:https://elifesciences.org/articles/12785
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