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High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis

Abstract: Burkitt lymphoma (BL), the most common pediatric cancer in sub-Saharan Africa, is a malignancy of antigen-experienced B lymphocytes. High-throughput sequencing (HTS) of the immunoglobulin heavy (IGH) and light chain (IGK/IGL) loci was performed on genomic DNA from 51 primary BL tumors: 19...

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Ngā kaituhi matua: Katharine A. Lombardo, David G. Coffey, Alicia J. Morales, Christopher S. Carlson, Andrea M.H. Towlerton, Sarah E. Gerdts, Francis K. Nkrumah, Janet Neequaye, Robert J. Biggar, Jackson Orem, Corey Casper, Sam M. Mbulaiteye, Kishor G. Bhatia, Edus H. Warren
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2017-03-01
Rangatū:Blood Advances
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2473952920301543
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