A cheminformatics and network pharmacology approach to elucidate the mechanism of action of Mycobacterium tuberculosis γ-carbonic anhydrase inhibitors

BackgroundMycobacterium tuberculosis (Mtb) carbonic anhydrases (CAs) are critical enzymes that regulate pH by converting CO2 to HCO3−, essential for Mtb’s survival in acidic environments. Inhibiting γ-CAs presents a potential target for novel antituberculosis drugs with unique mechanisms of action.O...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Ajay Manaithiya, Ratul Bhowmik, Kunal Bhattacharya, Rajarshi Ray, Sagar Singh Shyamal, Fabrizio Carta, Claudiu T. Supuran, Seppo Parkkila, Ashok Aspatwar
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2024-09-01
Saila:	Frontiers in Pharmacology
Gaiak:	Mycobacterium tuberculosis γ-CAs virtual screening system biology inflammatory responses
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1457012/full
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!