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Investigation of gyrA and parC mutations and the prevalence of plasmid-mediated quinolone resistance genes in Klebsiella pneumoniae clinical isolates

Abstract Background The emergence of fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae is a growing concern. To investigate the mechanisms behind this resistance, we studied a total of 215 K. pneumoniae isolates from hospitals in Bushehr province, Iran, collected between 2017...

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Main Authors: Sepideh Rezaei, Saeed Tajbakhsh, Behrouz Naeimi, Forough Yousefi
Format: Artigo
Language:Inglês
Published: BMC 2024-07-01
Series:BMC Microbiology
Subjects:
Fluoroquinolones
Klebsiella pneumoniae
Mutation
gyrA
parC
PMQR
Online Access:https://doi.org/10.1186/s12866-024-03383-5
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