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T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients

Abstract Background Polymyositis (PM) and dermatomyositis (DM) are two distinct subgroups of idiopathic inflammatory myopathies, a chronic inflammatory disorder clinically characterized by muscle weakness and inflammatory cell infiltrates in muscle tissue. In PM, a major component of inflammatory ce...

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Principais autores: Miranda Houtman, Louise Ekholm, Espen Hesselberg, Karine Chemin, Vivianne Malmström, Ann M. Reed, Ingrid E. Lundberg, Leonid Padyukov
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-08-01
coleção:Arthritis Research & Therapy
Assuntos:
Idiopathic inflammatory myopathies
Polymyositis
Dermatomyositis
T cells
CD4+ T cells
CD8+ T cells
Acesso em linha:http://link.springer.com/article/10.1186/s13075-018-1688-7
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