BCREval: a computational method to estimate the bisulfite conversion ratio in WGBS

Abstract Background Whole genome bisulfite sequencing (WGBS) also known as BS-seq has been widely used to measure the methylation of whole genome at single-base resolution. One of the key steps in the assay is converting unmethylated cytosines into thymines (BS conversion). Incomplete conversion of...

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Detalhes bibliográficos

Principais autores:	Junhua Zhou, Minqiong Zhao, Zefang Sun, Feilong Wu, Yucong Liu, Xianghua Liu, Zuping He, Quanze He, Quanyuan He
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-01-01
coleção:	BMC Bioinformatics
Assuntos:	DNA methylation Whole genome bisulfite sequencing (WGBS) Bisulfite conversion ratio (BCR) Telomere
Acesso em linha:	https://doi.org/10.1186/s12859-019-3334-z
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