CD24a knockout results in an enhanced macrophage- and CD8⁺ T cell-mediated anti-tumor immune responses in tumor microenvironment in a murine triple-negative breast cancer model

Abstract Background CD24 plays a crucial role not only in promoting tumor progression and metastasis but also in modulating macrophage-mediated anti-tumor immunity. However, its impact on the immune landscape of the tumor microenvironment (TME) remains unexplored. Here, we investigated the role of C...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Shih-Hsuan Chan, Chin-Yu Lin, Hsuan-Jung Tseng, Lu-Hai Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-08-01
Edice:	Journal of Biomedical Science
Témata:	CD24a CRISPR/Cas9 knockout Triple-negative breast cancer Tumor microenvironment Macrophages CD8+ T cells
On-line přístup:	https://doi.org/10.1186/s12929-025-01165-3
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!