Lactobacillus johnsonii and 3-indolepropionic acid improve the depression-like behaviors via inhibiting neuroinflammation

Gut microbiota-derived metabolites play a crucial role in depression. This study aimed to elucidate the role of tryptophan metabolites herein. In a CSDS mouse model, we identified eight differential species, twelve altered neurotransmitters, and two up-regulated inflammatory factors (IL-6 and IL-1β)...

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Detalhes bibliográficos

Principais autores:	Jing Xie, Yongzhi Zhang, Jiao-lin Wang, Fei He, Ke Xu, Jianjun Chen, Peng Xie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-04-01
coleção:	Pharmacological Research
Assuntos:	Depression Lactobacillus johnsonii 3-indolepropionic acid Inflammation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1043661826000733
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