Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model

DDX41 is an important sensor for host recognition of DNA viruses and initiation of nuclear factor-κB (NF-κB) and IFN signaling pathways in mammals. However, its occurrence and functions in other vertebrates remain poorly defined. Here, a DDX41 ortholog [Danio rerio DDX41 (DrDDX41)] with various cons...

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Principais autores:	Jun-xia Ma, Jiang-yuan Li, Dong-dong Fan, Wei Feng, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-06-01
coleção:	Frontiers in Immunology
Assuntos:	zebrafish DDX41 stimulator of IFN genes protein signal transduction and activator of transcription 6 nuclear factor-κB interferon
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01327/full
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