Association between single-nucleotide polymorphisms in endochondral development-related genes and 3D phenotypic variation of the cranial base

Abstract Background This study aimed to evaluate the association between single nucleotide polymorphisms (SNPs) in endochondral development-related genes and cranial base 3D phenotypes. Methods CBCT scans and the genomic DNA of 118 individuals were evaluated (age range: 15–66 years; 82 females). Dat...

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Автори:	Guido Artemio Marañón-Vásquez, Mônica Tirre de Souza Araújo, Antônio Carlos de Oliveira Ruellas, Mírian Aiko Nakane Matsumoto, Alejandro David Avalos Chávez, Marcio Figueiredo, Thaís de Oliveira Fernandes, Lívia Azeredo Alves Antunes, Manuel Lagravère Vich, Rafaela Scariot, Carlos Flores-Mir, Christian Kirschneck, Leonardo dos Santos Antunes, Erika Calvano Küchler
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2026-07-01
Серія:	Head & Face Medicine
Предмети:	Skull Base Polymorphism, Single Nucleotide BMP2 protein, human BMP4 protein, human RUNX2 protein, human Core Binding Factor Alpha 1 Subunit
Онлайн доступ:	https://doi.org/10.1186/s13005-026-00644-8
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Association between single-nucleotide polymorphisms in endochondral development-related genes and 3D phenotypic variation of the cranial base

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