Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus.

Podocyte or endothelial cell VEGF-A knockout causes thrombotic microangiopathy in adult mice. To study the mechanism involved in acute and local injury caused by low podocyte VEGF-A we developed an inducible, podocyte-specific VEGF-A knockdown mouse, and we generated an immortalized podocyte cell li...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Delma Veron, Guillermo Villegas, Pardeep Kumar Aggarwal, Claudia Bertuccio, Juan Jimenez, Heino Velazquez, Kimberly Reidy, Dale R Abrahamson, Gilbert Moeckel, Michael Kashgarian, Alda Tufro
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC3396653?pdf=render
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