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Systemic and Intestinal Viral Reservoirs in CD4+ T Cell Subsets in Primary SIV Infection

The HIV reservoir size in target CD4+ T cells during primary infection remains unknown. Here, we sorted peripheral and intestinal CD4+ T cells and quantified the levels of cell-associated SIV RNA and DNA in rhesus macaques within days of SIVmac251 inoculation. As a major target cell of HIV/SIV, CD4+...

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Autori principali: Xiaolei Wang, Widade Ziani, Ronald S. Veazey, Huanbin Xu
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-11-01
Serie:Viruses
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Accesso online:https://www.mdpi.com/1999-4915/13/12/2398
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