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Semaphorin‐3C signals through Neuropilin‐1 and PlexinD1 receptors to inhibit pathological angiogenesis

Abstract Retinopathy of prematurity causes visual impairment due to destructive neoangiogenesis after degeneration of the retinal microvasculature. This study was aimed at analyzing whether local delivery of Semaphorin‐3C (Sema3C) suppresses pathological retinal angiogenesis. Sema3C exerted potent i...

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Principais autores: Wan‐Jen Yang, Junhao Hu, Akiyoshi Uemura, Fabian Tetzlaff, Hellmut G Augustin, Andreas Fischer
Format: Artigo
Jezik:Inglês
Izdano: Springer Nature 2015-07-01
Serija:EMBO Molecular Medicine
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Online dostop:https://doi.org/10.15252/emmm.201404922
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