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Plasmodium apicoplast tyrosyl-tRNA synthetase recognizes an unusual, simplified identity set in cognate tRNATyr.

The life cycle of Plasmodium falciparum, the agent responsible for malaria, depends on both cytosolic and apicoplast translation fidelity. Apicoplast aminoacyl-tRNA synthetases (aaRS) are bacterial-like enzymes devoted to organellar tRNA aminoacylation. They are all encoded by the nuclear genome and...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Marta Cela, Caroline Paulus, Manuel A S Santos, Gabriela R Moura, Magali Frugier, Joëlle Rudinger-Thirion
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2018-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0209805
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