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Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1.

The neural cell adhesion molecule L1 is critical for brain development and plays a role in learning and memory in the adult. Ethanol inhibits L1-mediated cell adhesion and neurite outgrowth in cerebellar granule neurons (CGNs), and these actions might underlie the cerebellar dysmorphology of fetal a...

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Autori principali: Devon M Fitzgerald, Michael E Charness, Kimberly A Leite-Morris, Suzhen Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3169602?pdf=render
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